Friday’s Big South college basketball schedule includes top teams in play. Among those contests is the Winthrop Eagles squaring off against the Louisville Cardinals, and we have predictions against the spread right here for all the matchups.

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Big South Picks ATS Today

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Pick: Longwood +6.5 vs. UAB

• Matchup: Longwood Lancers vs. UAB Blazers
• Projected Favorite & Spread: Longwood by 3 points (Bet on BetMGM)
• Spread: UAB -6.5
• Time: 12:30 PM ET
• Date: November 22
• TV Channel: ESPN Networks

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Pick: Presbyterian +6.5 vs. Youngstown State

• Matchup: Presbyterian Blue Hose vs. Youngstown State Penguins
• Projected Favorite & Spread: Youngstown State by 4.2 points (Bet on BetMGM)
• Spread: Youngstown State -6.5
• Time: 3:30 PM ET
• Date: November 22
• TV Channel: ESPN+
• Live Stream: ESPN+

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Pick: Winthrop +16.5 vs. Louisville

• Matchup: Winthrop Eagles at Louisville Cardinals
• Projected Favorite & Spread: Louisville by 14.5 points (Bet on BetMGM)
• Spread: Louisville -16.5
• Time: 7:00 PM ET
• Date: November 22
• TV Channel: ACC Network Extra

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